biomedicina slovenica


"SUBSTRATE SPECIFICITY" : 59

  1. Ačimovič Jure; Rozman Damjana
    Steroidal triterpenes of cholesterol synthesis
    2013
  2. Cassetta Alberto; Krastanova Ivet; Kristan Katja; Brunskole Mojca; Lamba Doriano; Lanišnik-Rižner Tea; Stojan Jure
    Insights into subtle conformational differences in the substrate-binding loop of fungal 17beta-hydroxysteroid dehydrogenase: a combined structural and kinetic approach
    2012
  3. Kristan Katja; Lanišnik-Rižner Tea
    Steroid-transforming enzymes in fungi
    2012
  4. Lah Ljerka; Podobnik Barbara; Novak Metka; Korošec Branka; Berne Sabina; Vogelsang Matjaž; Kraševec Nada; Zupanec Neja; Stojan Jure; Bohlmann Joerg; Komel Radovan
    The versatility of the fungal cytochrome P450 monooxygenase system is instrumental in xenobiotic detoxication
    2011
  5. Brunskole-Švegelj Mojca; Stojan Jure; Lanišnik-Rižner Tea
    The role of Ala231 and Trp227 in the substrate specificities of fungal 17beta-hydroxysteroid dehydrogenase and trihydroxynaphthalene reductase: steroids versus smaller substrates
    2012
  6. Munch-Petersen Birgitte; Piškur Jure; Sondergaard Leif
    Four deoxynucleoside kinase activities from Drosophila melanogaster are contained within a single monomeric enzyme, a new multifunctional deoxynucleoside kinase
    1998
  7. Munch-Petersen Birgitte; Knecht Wolfgang; Lenz Camilla; Sondergaard Leif; Piškur Jure
    Functional expression of a multisubstrate deoxyribonucleoside kinase from Drosophila melanogaster and its C-terminal deletion mutants
    2000
  8. Knecht Wolfgang; Munch-Petersen Birgitte; Piškur Jure
    Identification of residues involved in the specificity and regulation of the highly efficient multisubstrate deoxyribonucleoside kinase from Drosophila melanogaster
    2000
  9. Johansson Kenth; Ramaswamy S; Ljungcrantz Catarina; Knecht Wolfgang; Piškur Jure; Munch-Petersen Birgitte; Eriksson Staffan; Eklund Hans
    Structural basis for substrate specificities of cellular deoxyribonucleoside kinases
    2001
  10. Knecht Wolfgang; Sandrini Michael PB; Johansson Kenth; Eklund Hans; Munch-Petersen Birgitte; Piškur Jure
    A few amino acid substitutions can convert deoxyribonucleoside kinase specificity from pyrimidines to purines
    2002
  11. Ullrich Alexandra; Knecht Wolfgang; Piškur Jure; Loffler Monika
    Plant dihydroorotate dehydrogenase differs significantly in substrate specificity and inhibition from the animal enzymes
    2002
  12. Knecht W; Petersen GE; Munch-Petersen B; Piškur J
    Deoxyribonucleoside kinases belonging to the thymidine kinase 2 (TK2)-like group vary significantly in substrate specificity, kinetics and feed-back regulation
    2002
  13. Knecht Wolfang; Petersen Gitte Ebert; Sandrini Michael P; Sondergaard Leif; Munch-Petersen Birgitte; Piškur Jure
    Mosquito has a single multisubstrate deoxyribonucleoside kinase characterized by unique substrate specificity
    2003
  14. Gojkovic Zoran; Rislund Lise; Andersen Birgit; Sandrini Michael P; Cook Paul F; Schnackerz Klaus D; Piškur Jure
    Dihydropyrimidine amidohydrolases and dihydroorotases share the same origin and several enzymatic properties
    2003
  15. Piškur Jure; Sandrini Michael P; Knecht Wolfgang; Munch-Petersen Birgitte
    Animal deoxyribonucleoside kinases: 'forward' and 'retrograde' evolution of their substrate specificity
    2004
  16. Sandrini Michael P; Piškur Jure
    Deoxyribonucleoside kinases: two enzyme families catalyze the same reaction
    2005
  17. Welin Martin; Skovgaard Tine; Knecht Wolfgang; Zhu Chunying; Berenstein Dvora; Munch-Petersen Birgitte; Piškur Jure; Eklund Hans
    Structural basis for the changed substrate specificity of Drosophila melanogaster deoxyribonucleoside kinase mutant N64D
    2005
  18. Lohkamp Bernhard; Andersen Birgit; Piškur Jure; Dobritzsch Doreen
    The crystal structures of dihydropyrimidinases reaffirm the close relationship between cyclic amidohydrolases and explain their substrate specificity
    2006
  19. Zameitat Elke; Gojković Zoran; Knecht Wolfgang; Piškur Jure; Loffler Monika
    Biochemical characterization of recombinant dihydroorotate dehydrogenase from the opportunistic pathogenic yeast Candida albicans
    2006
  20. Andersen Gorm; Andersen Birgit; Dobritzsch Doreen; Schnackerz Klaus D; Piškur Jure
    A gene duplication led to specialized gamma-aminobutyrate and beta-alanine aminotransferase in yeast
    2007
  21. Sandrini Michael Paolo; Soederbom Fredrik; Mikkelsen Nils Egill; Piškur Jure
    Dictyostelium discoideum salvages purine deoxyribonucleosides by highly specific bacterial-like deoxyribonucleoside kinases
    2007
  22. Sandrini Michael P; Clausen Anders R; On Stephen LW; Aarestrup Frank M; Munch-Petersen Birgitte; Piškur Jure
    Nucleoside analogues are activated by bacterial deoxyribonucleoside kinases in a species-specific manner
    2007
  23. Knecht W; Rozpedowska E; Le Breton C; Willer M; Gojkovic Z; Sandrini MP; Joergensen T; Hasholt L; Munch-Petersen B; Piškur J
    Drosophila deoxyribonucleoside kinase mutants with enhanced ability to phosphorylate purine analogs
    2007
  24. Clausen Anders Ranegaard; Girandon Lenart; Knecht Wolfgang; Survery Sabeen; Andreasson Erik; Munch-Petersen BBirgitte; Piškur Jure
    A multisubstrate deoxyribonucleoside kinase from plants
    2008
  25. Kristan Katja; Brunskole Mojca; Stojan Jure; Lanišnik-Rižner Tea
    Two homologous fungal carbonyl reductases with different substrate specificities
    2009
  26. Kristan Katja; Stojan Jure; Adamski Jerzy; Lanišnik-Rižner Tea
    Rational design of novel mutants of fungal 17beta-hydroxysteroid dehydrogenase
    2007
  27. Colletier Jacques-Philippe; Fournier Didier; Greenblatt Harry M; Stojan Jure; Sussman Joel L; Zaccai Giuseppe; Silman Israel; Weik Martin
    Structural insights into substrate traffic and inhibition in acetylcholinesterase
    2006
  28. Holm C; Contreras JA; Verger R; Schotz MC
    Large-scale purification and kinetic properties of recombinant hormone-sensitive lipase from baculovirus-insect cell systems
    1997
  29. Osterlund T; Danielsson B; Degerman E; Contreras JA; Edgren G; Davis RC; Schotz MC; Holm C
    Domain-structure analysis of recombinant rat hormone-sensitive lipase
    1996
  30. Kristan Katja; Kovačič Brina; Stojan Jure; Adamski Jerzy; Lanišnik-Rižner Tea
    Further insight into the structural basis of coenzyme and substrate specificity of fungal 17beta-hydroxysteroid dehydrogenase
    2006
  31. Kristan Katja
    Povezava med strukturo in delovanjem glivne 17beta-hidroksisteroid-dehidrogenaze, modelnega encima naddružine kratkoverižnih dehidrogenaz/reduktaz
    [Structure/function relationship in fungual 17beta-hydroxysteroid dehydrogenase, a model enzyme of the short-chain dehydrogenase/reductase superfamily]
    2005
  32. Stojan Jure
    Enzyme inhibitors
    2004
  33. Stojan Jure; Brochier Laure; Alies Carole; Colletier Jacques Philippe; Fournier Didier
    Inhibition of Drosophila melanogaster acetylcholinesterase by high concentations of substrate
    2004
  34. Kristan Katja; Kovačič Brina; Stojan Jure; Lanišnik-Rižner Tea
    Further insight into coenzyme and substrate specificity of fungal 17 beta-hydroxysteroid dehydrogenase
    2004
  35. Gruden Kristina; Popovič Tatjana; Cimerman Nina; Križaj Igor; Štrukelj Borut
    Diverse enzymatic specificities of digestive proteases, 'Intestains', enable Colorado potato beetle larvae to counteract the potato defence mechanism
    2003
  36. Bresjanac Mara; Šmid Lojze M; Vovko Tomaž D; Petrič Andrej; Barrio Jorge R; Popović Mara
    Molecular-imaging probe-2-(1-(6-((2-fluoroethyl)(mathyl)amino)-2-naphthyl)ethylidene) malononitrile labels prion plaques in vitro
    2003
  37. Kristan Katja; Lanišnik-Rižner Tea; Stojan Jure; Gerber Josef K; Kremmer Elisabeth; Adamski Jerzy
    Significance of individual amino acid residues for coenzyme and substrate specificity of 17beta-hydroxysteroid dehydrogenase from the fungus Cochliobolus lunatus
    2003
  38. Rozman-Pungečar Jerica; Kopitar-Jerala Nataša; Baruch Amos; Turk Dušan; Vassilieva Olga S; Štefe Ivica; Vandenabeele Peter; Broemme Dieter; Puizdar Vida; Fonovič Marko; Trstenjak-Prebanda Mojca; Dolenc Iztok; Bogyo Matthew; Turk Vito; Turk Boris
    When reaction mechanisms is more important than substrate specificity: inhibition of papain-like cysteine proteases and legumain by "caspase-specific" inhibitors
    2002
  39. Podust Larisa M; Stojan Jure; Poulos Thomas L; Waterman Michael R
    Substrate recognition sites in 14alpha-sterol demethylase from comparative analysis of amino acid sequences and X-ray structure of Mycobacterium tuberculosis CYP51
    2001
  40. Collen D; Lijnen HR
    Recent developments in thrombolytic therapy
    2001
  41. Lanišnik-Rižner T; Stojan J; Adamski J
    17beta-hydroxysteroid dehydrogenase from the fungus Cochliobolus lunatus: structural and functional aspects
    2001
  42. Gruden Kristina; Jongsma Maarten A; Herzog-Velikonja Blagajana; Štrukelj Borut
    Adaptation of Colorado potato beetle to plant defense mechanism
    [Adaptacija koloradskega hrošča na obrambni mehanizem rastlin]
    2000
  43. Lanišnik-Rižner Tea; Adamski Jerzy; Stojan Jure
    17beta-hydroxysteroid dehydrogenase from Cochliobolus lunatus: model structure and substrate specificity
    2000
  44. Lanišnik-Rižner T; Stojan J; Adamski J
    Searching for the physiological function of 17beta-hydroxysteroid dehydrogenase from the fungus Cochliobolus lunatus: studies of substrate specificity and expression analysis
    2001
  45. Lanišnik-Rižner Tea; Stojan Jure
    17beta-hydroxysteroid dehydrogenase from Cochliobolus lunatus: model structure and substrate specificity
    2000
  46. Stubbs Simon; Rupnik Maja; Gibert Maryse; Brazier Jon; Duerden Brian; Popoff Michel
    Production of actin-specific ADP-ribosyltransferase (binary toxin) by strains of Clostridium difficile
    2000
  47. Zorko Matjaž; Gottlieb HE; Žakelj-Mavrič Marija
    Pluripotency of 17beta-hydroxysteroid dehydrogenase from the filamentous fungus Cochliobolus lunatus
    2000
  48. Werle Bernd; Staib Alexander; Juelke Britta; Ebert Werner; Zladoidsky Pavel; Sekirnik Andreja; Kos Janko; Spiess Eberhard
    Fluorometric microassays for the determination of cathepsin L and capthepsin S activities in tissue extracts
    1999
  49. Pogačar Martina
    Ločitev in delna karakterizacija 17beta-hidroksisteroidne dehidrogenaze in beta-hidroksibutiril CoA dehidrogenaze iz glive Pleurotus ostreatus
    1999
  50. Jakša Nataša
    Substratna specifičnost 17 beta-hidroksisteroidne dehidragonaze iz glive Cochliobolus lunatus
    [Substrate specificity of 17 beta-hydroxysteroid dehydrogenase from the fungus Cochliobolus lunatus]
    1995
  51. Kos Janko; Lah Tamara T
    Cysteine proteinases and their endogenous inhibitors: target proteins for prognosis, diagnosis and therapy in cancer (review)
    1998
  52. Lah Tamara T; Kos Janko
    Cysteine proteinases in cancer progression and their clinical relevance for prognosis
    1998
  53. Pogačar M; Zorko M; Žakelj-Mavrič M
    Substrate specificity of 17 beta-hydroxysteroid dehydrogenase from Pleurotus ostreatus
    1998
  54. Pogačar M; Lanišnik-Rižner T; Zorko M; Žakelj-Mavrič M
    Substrate specificity of 17beta-hydroxysteroid dehydrogenase from Pleurotus ostreatus
    1997
  55. Lenasi H; Hudnik-Plevnik T
    Identification and partial characterization of cytosolic progesterone-binding sites in the filamentous fungus Rhizopus nigricans
    1996
  56. Buttle DJ; Ritonja A; Pearl LH; Turk V; Barrett AJ
    Selective cleavage of glycyl bonds by papaya proteinase IV
    1990
  57. Madrid-Marina V; Lestan B; Nowak PJ; Fox IH; Spychala J
    Altered properties of human T-lymphoblast soluble low Km 5'-nucleotidase: comparison with B-lymphoblast enzyme
    1993
  58. Breskvar K
    The properties of cytochrome P-450 induced in the rat small intestine by estradiol
    1986
  59. Blinc Aleš; Francis Charles W; Trudnowski Janet L; Carstensen Edwin L
    Characterization of ultrasound-potentiated fibrinolysis in vitro
    1993



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